Publications

Robison TH, Lee W, Luker KE, Pettit K, Talpaz M, Chenevert TL, Ross BD, Luker GD. Quantitative MRI reveals heterogeneous impacts of treatment on diseased bone marrow in a mouse model of myelofibrosis. Magn Reson Med. 2024 Jan 24. doi: 10.1002/mrm.30016. Epub ahead of print. PMID: 38265182. 

Robison T, Levinson A, Lee W, Pettit KM, Malyarenko D, Johnson TD, Chenevert TL, Ross B, Talpaz M, Luker G. MRI Reliably Captures Bone Marrow Metrics in Myelofibrosis. Blood (2023) 142 (Supplement 1): 4556. https://doi.org/10.1182/blood-2023-189869 

Moore SM, Quirk JD, Lassiter AW, Laforest R, Ayers GD, Badea CT, Fedorov AY, Kinahan PE, Holbrook M, Larson PEZ, Sriram R, Chenevert TL, Malyarenko D, Kurhanewicz J, Houghton AM, Ross BD, Pickup S, Gee JC, Zhou R, Gammon ST, Manning HC, Roudi R, Daldrup-Link HE, Lewis MT, Rubin DL, Yankeelov TE, Shoghi KI. Co-Clinical Imaging Metadata Information (CIMI) for Cancer Research to Promote Open Science, Standardization, and Reproducibility in Preclinical Imaging. Tomography. 2023 May 11;9(3):995-1009. doi: 10.3390/tomography9030081. PMID: 37218941; PMCID: PMC10204428. 

Gammon ST, Cohen AS, Lehnert AL, Sullivan DC, Malyarenko D, Manning HC, Hormuth DA, Daldrup-Link HE, An H, Quirk JD, Shoghi K, Pagel MD, Kinahan PE, Miyaoka RS, Houghton AM, Lewis MT, Larson P, Sriram R, Blocker SJ, Pickup S, Badea A, Badea CT, Yankeelov TE, Chenevert TL. An Online Repository for Pre-Clinical Imaging Protocols (PIPs). Tomography. 2023 Mar 27;9(2):750-758. doi: 10.3390/tomography9020060. PMID: 37104131; PMCID: PMC10145184. 

Kushwaha A, Mourad RF, Heist K, Tariq H, Chan HP, Ross BD, Chenevert TL, Malyarenko D, Hadjiiski LM. Improved Repeatability of Mouse Tibia Volume Segmentation in Murine Myelofibrosis Model Using Deep Learning. Tomography. 2023 Mar 7;9(2):589-602. doi: 10.3390/tomography9020048. PMID: 36961007; PMCID: PMC10037585. 

Ross BD, Malyarenko D, Heist K, Amouzandeh G, Jang Y, Bonham CA, Amirfazli C, Luker GD, Chenevert TL. Repeatability of Quantitative Magnetic Resonance Imaging Biomarkers in the Tibia Bone Marrow of a Murine Myelofibrosis Model. Tomography. 2023 Feb 28;9(2):552-566. doi: 10.3390/tomography9020045. PMID: 36961004; PMCID: PMC10037563. 

Malyarenko D, Amouzandeh G, Pickup S, Zhou R, Manning HC, Gammon ST, Shoghi KI, Quirk JD, Sriram R, Larson P, Lewis MT, Pautler RG, Kinahan PE, Muzi M, Chenevert TL. Evaluation of Apparent Diffusion Coefficient Repeatability and Reproducibility for Preclinical MRIs Using Standardized Procedures and a Diffusion-Weighted Imaging Phantom. Tomography. 2023 Feb 7;9(1):375-386. doi: 10.3390/tomography9010030. PMID: 36828382; PMCID: PMC9964373. 

Zhou M, Ma Y, Chiang CC, Rock EC, Luker KE, Luker GD, Chen YC. High-Throughput Cellular Heterogeneity Analysis in Cell Migration at the Single-Cell Level. Small. 2023 Feb;19(6):e2206754. doi: 10.1002/smll.202206754. Epub 2022 Nov 30. PMID: 36449634; PMC9908848. 

Kinnunen PC, Luker GD, Luker KE, Linderman JJ. Computational modeling implicates protein scaffolding in p38 regulation of Akt. J Theor Biol. 2022 Dec 21;555:111294. doi: 10.1016/j.jtbi.2022.111294. Epub 2022 Oct 1. PMID: 36195198

Robison TH, Solipuram M, Heist K, Amouzandeh G, Lee WY, Humphries BA, Buschhaus JM, Bevoor A, Zhang A, Luker KE, Pettit K, Talpaz M, Malyarenko D, Chenevert TL, Ross BD, Luker GD. Multiparametric MRI to quantify disease and treatment response in mice with myeloproliferative neoplasms. JCI Insight. 2022 Oct 10;7(19):e161457. doi: 10.1172/jci.insight.161457. PMC9675444 

Ross BD, Jang Y, Welton A, Bonham CA, Palagama DSW, Heist K, Boppisetti J, Imaduwage KP, Robison T, King LR, Zhang EZ, Amirfazli C, Luker KE, Lee WY, Luker GD, Chenevert TL, Van Dort ME. A lymphatic-absorbed multi-targeted kinase inhibitor for myelofibrosis therapy. Nat Commun. 2022 Aug 17;13(1):4730. doi: 10.1038/s41467-022-32486-8. PMC9386018

Buschhaus JM, Rajendran S, Humphries BA, Cutter AC, Muñiz AJ, Ciavattone NG, Buschhaus AM, Cañeque T, Nwosu ZC, Sahoo D, Bevoor AS, Shah YM, Lyssiotis CA, Ghosh P, Wicha MS, Rodriguez R, Luker GD. Effects of iron modulation on mesenchymal stem cell-induced drug resistance in estrogen receptor-positive breast cancer. Oncogene. 2022 Jul;41(29):3705-3718. doi: 10.1038/s41388-022-02385-9. Epub 2022 Jun 22. PMC9288981 

Luker KE, Luker GD. The CXCL12/CXCR4/ACKR3 Signaling Axis Regulates PKM2 and Glycolysis. Cells. 2022 May 28;11(11):1775. doi: 10.3390/cells11111775. PMC9179862

Amouzandeh G, Chenevert TL, Swanson SD, Ross BD, Malyarenko DI. Technical note: Temperature and concentration dependence of water diffusion in polyvinylpyrrolidone solutions. Med Phys. 2022 May;49(5):3325-3332. doi: 10.1002/mp.15556. Epub 2022 Mar 3. PMC9090959 

Van Dort ME, Jang Y, Bonham CA, Heist K, Palagama DSW, McDonald L, Zhang EZ, Chenevert TL, Luker GD, Ross BD. Structural effects of morpholine replacement in ZSTK474 on Class I PI3K isoform inhibition: Development of novel MEK/PI3K bifunctional inhibitors. Eur J Med Chem. 2022 Feb 5;229:113996. doi: 10.1016/j.ejmech.2021.113996. Epub 2021 Nov 14. PMC8792322

Malyarenko DI, Swanson SD, McGarry SD, LaViolette PS, Chenevert TL. The impeded diffusion fraction quantitative imaging assay demonstrated in multi-exponential diffusion phantom and prostate cancer. Magn Reson Med. 2022 Apr;87(4):2053-2062. doi: 10.1002/mrm.29075. Epub 2021 Nov 14. PMID: 34775621, PMC8810585

Spinosa PC, Kinnunen PC, Humphries BA, Luker GD, Luker KE, Linderman JJ. Pre-existing Cell States Control Heterogeneity of Both EGFR and CXCR4 Signaling. Cell Mol Bioeng. 2020 Jul 27;14(1):49-64. doi: 10.1007/s12195-020-00640-1. PMC7878609

Hu HH, Yokoo T, Bashir MR, Sirlin CB, Hernando D, Malyarenko D, Chenevert TL, Smith MA, Serai SD, Middleton MS, Henderson WC, Hamilton G, Shaffer J, Shu Y, Tkach JA, Trout AT, Obuchowski N, Brittain JH, Jackson EF, Reeder SB; RSNA Quantitative Imaging Biomarkers Alliance PDFF Biomarker Committee. Linearity and Bias of Proton Density Fat Fraction as a Quantitative Imaging Biomarker: A Multicenter, Multiplatform, Multivendor Phantom Study. Radiology. 2021 Mar;298(3):640-651. doi: 10.1148/radiol.2021202912. Epub 2021 Jan 19. PMC7924516

Luker GD. Imaging the Immune Tumor Microenvironment to Monitor and Improve Therapy. Radiology. 2021 Jan;298(1):133-134. doi: 10.1148/radiol.2020203799. Epub 2020 Oct 27. PMC7771989 

Shoghi KI, Badea CT, Blocker SJ, Chenevert T, Laforest R, Lewis MT, Luker GD, Manning HC, Marcus DS, Mowery YM, Pickup S, Richmond A, Ross B, Vilgelm AE, Yankeelov TE, Zhou R. Co-Clinical Imaging Resource Program (CIRP): Bridging the translational divide to advance precision medicine. Tomography. 2020;6(3):273-287. PMC7442091

Malyarenko D, Ono S, Lynch TJE, Swanson SD. Technical note: hydrogel-based mimics of prostate cancer with matched relaxation, diffusion and kurtosis for validating multi-parametric MRI. Med Phys. 2023 Dec 21. doi: 10.1002/mp.16908. Epub ahead of print. PMID: 38128027. 

Shukla-Dave A, Obuchowski NA, Chenevert TL, Jambawalikar S, Schwartz LH, Malyarenko D, Huang W, Noworolski SM, Young RJ, Shiroishi MS, Kim H, Coolens C, Laue H, Chung C, Rosen M, Boss M, Jackson EF. Quantitative imaging biomarkers alliance (QIBA) recommendations for improved precision of DWI and DCE-MRI derived biomarkers in multicenter oncology trials. J Magn Reson Imaging. 2019 Jun;49(7):e101-e121. PMC6526078

Malyarenko DI, Swanson SD, Konar AS, LoCastro E, Paudyal R, Liu MZ, Jambawalikar SR, Schwartz LH, Shukla-Dave A, Chenevert TL. Multicenter repeatability study of a novel quantitative diffusion kurtosis imaging phantom. Tomography. 2019 Mar;5(1):36-43. PMC6403043

Heckman KM, Otemuyiwa B, Chenevert TL, Malyarenko D, Derstine BA, Wang SC, Davenport MS. Validation of a DIXON-based fat quantification technique for the measurement of visceral fat using a CTbased reference standard. Abdom Radiol (NY). 2019 Jan;44(1):346-354. PMID29946923

Schaefer J, Choi S, Luker G, Chenevert T, Ross B, Talpaz M. Primary myelofibrosis evolving to an aplastic appearing marrow. Clin Case Rep. 2018 May 31;6(7):1393-1395. PMC6028358

deSouza NM, Winfield JM, Waterton JC, Weller A, Papoutsaki MV, Doran SJ, Collins DJ, Fournier L, Sullivan D, Chenevert T, Jackson A, Boss M, Trattnig S, Liu Y. Implementing diffusion-weighted MRI for body imaging in prospective multicentre trials: current considerations and future perspectives. Eur Radiol. 2018 Mar;28(3):1118-1131. PMC5811587

Keenan KE, Ainslie M, Barker AJ, Boss MA, Cecil KM, Charles C, Chenevert TL, Clarke L, Evelhoch JL, Finn P, Gembris D, Gunter JL, Hill DLG, Jack CR, Jr., Jackson EF, Liu G, Russek SE, Sharma SD, Steckner M, Stupic KF, Trzasko JD, Yuan C, Zheng J. Quantitative magnetic resonance imaging phantoms: A review and the need for a system phantom. Magn Reson Med. 2018 Jan;79(1):48-61. PMID29083101

O'Connor JP, Aboagye EO, Adams JE, Aerts HJ, Barrington SF, Beer AJ, Boellaard R, Bohndiek SE, Brady M, Brown G, Buckley DL, Chenevert TL, Clarke LP, Collette S, Cook GJ, deSouza NM, Dickson JC, Dive C, Evelhoch JL, Faivre-Finn C, Gallagher FA, Gilbert FJ, Gillies RJ, Goh V, Griffiths JR, Groves AM, Halligan S, Harris AL, Hawkes DJ, Hoekstra OS, Huang EP, Hutton BF, Jackson EF, Jayson GC, Jones A, Koh DM, Lacombe D, Lambin P, Lassau N, Leach MO, Lee TY, Leen EL, Lewis JS, Liu Y, Lythgoe MF, Manoharan P, Maxwell RJ, Miles KA, Morgan B, Morris S, Ng T, Padhani AR, Parker GJ, Partridge M, Pathak AP, Peet AC, Punwani S, Reynolds AR, Robinson SP, Shankar LK, Sharma RA, Soloviev D, Stroobants S, Sullivan DC, Taylor SA, Tofts PS, Tozer GM, van Herk M, Walker-Samuel S, Wason J, Williams KJ, Workman P, Yankeelov TE, Brindle KM, McShane LM, Jackson A, Waterton JC. Imaging biomarker roadmap for cancer studies. Nat Rev Clin Oncol. 2017 Mar;14(3):169-186. PMC5378302

Luker G, Nguyen H, Hoff B, Galban C, Hernando D, Chenevert T, Talpaz M, Ross B. A pilot study of Quantitative MRI parametric response mapping of bone marrow fat for treatment assessment in myelofibrosis. Tomography. 2016 Mar;2(1):67-78. PMC4872873

Malyarenko DI, Zimmermann EM, Adler J, Swanson SD. Magnetization transfer in lamellar liquid crystals. Magn Reson Med. 2014 Nov;72(5):1427-34. PMC4028438

Malyarenko D, Galban CJ, Londy FJ, Meyer CR, Johnson TD, Rehemetulla A, Ross BD, Chenevert TL. Multi-system repeatability and reproducibility of apparent diffusion coefficient measurement using an ice-water phantom. J Magn Reson Imaging. 2013 May;37(5):1238-46. PMC3548033

Verstovsek S, Mesa R, Gotlib J, Levy R, Gupta V, DiPersio J, Catalano J, Deininger M, Miller C, Silver R, Talpaz M, Winton E, Harvey JJ, Arcasoy M, Hexner E, Lyons R, Paquette R, Raza A, Vaddi K, ERickson-Viitanen S, Koumenis I, Sun W, Sandor V, Kantarjian H. A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis. N Engl J Med. 2012;366(9):799-807. PMC4822164

Adler J, Swanson S, Schmiedlin-Ren P, Higgins P, Golembeski C, Polydorides A, Mckenna B, Hussain H, Verrot T, Zimmermann E. Magnetization transfer helps detect intestinal fibrosis in an animal model of Crohn disease. Radiology. 2011 Apr;259(1):127-35. PMC3064818 .